Association Between Bicuspid Aortic Valve Phenotype and Patterns of Valvular Dysfunction and Bicuspid Aortopathy
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چکیده
منابع مشابه
Bicuspid Aortic Valve-associated Aortopathy
Patients with bicuspid aortic valve (BAV) have an increased risk of developing ascending aortic aneurysm compared with individuals with a tricuspid aortic valve (TAV). A crucial factor involved in vascular remodeling during aneurysm development is transforming growth factor-β (TGF-β) and impaired signaling of this pathway can alter important extracellular matrix (ECM) protein such us fibronecti...
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Bicuspid aortic valve (BAV) is the most common congenital valvular defect and is associated with ascending aortic dilation (AAD) in a quarter of patients. AAD has been ascribed both to the hemodynamic consequences of normally functioning and abnormal BAV morphology, and to the effect of rare and common genetic variation upon function of the ascending aortic media. AAD manifests in two overall a...
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The association between ascending aortic aneurysm (AA) and bicuspid aortic valve (BAV) has been well established. Different genetic, haemodynamic and cardiovascular risk factors have been implicated in the development and progression of AA. However, to date, definite conclusions cannot be drawn regarding the exact molecular, cellular and haemodynamic mechanisms causing BAV-associated aortopathy...
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The regurgitant volume of TR might increase dynamically despite unchanged effective regurgitant orifice area, thus exaggerating TR severity on echocardiographic assessment. Meanwhile, functional TR from various chronic and acute cardiomyopathies may significantly reverse either by itself or after medical treatment. Thus, integrated analysis on both cardiac imaging and clinical data of functiona...
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Bicuspid aortic valve (BAV) is the most common form of congenital heart disease and most such patients develop cardiovascular complications over time. Recent studies have shed light on one of the most common of these complications, BAV-associated aortopathy. Two distinct BAV phenotypes have been identified, which may have different causes of their associated aortopathy. Increasing evidence sugg...
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ژورنال
عنوان ژورنال: JACC: Cardiovascular Imaging
سال: 2013
ISSN: 1936-878X
DOI: 10.1016/j.jcmg.2012.11.007